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Writer's pictureWellness Team

Iatrogenic Menopause: Causes, Symptoms, and Treatment

Updated: 3 days ago

Menopause is often thought of as a natural part of aging, but for some women, it arrives earlier and more suddenly than expected, due to medical interventions. This is known as iatrogenic menopause. Understanding the causes, symptoms, and treatment options for iatrogenic menopause is essential for those affected, as its sudden onset can pose unique challenges. This blog aims to provide clarity on what iatrogenic menopause is, its impact on women, and strategies for managing its effects.


What is Iatrogenic Menopause?


Iatrogenic menopause occurs when medical treatments or procedures induce menopause before the natural cessation of ovarian function. Unlike natural menopause, which typically occurs between ages 45 and 55 as a gradual decline in reproductive hormones, iatrogenic menopause often brings a rapid decrease in estrogen levels, leading to an abrupt onset of symptoms.


Common causes of iatrogenic menopause include:


  • Surgical Removal of Ovaries (Oophorectomy): This is one of the most common causes of iatrogenic menopause. When one or both ovaries are removed—often due to conditions like ovarian cancer, endometriosis, or severe pelvic inflammatory disease—hormone production is halted, triggering menopause.


  • Cancer Treatments: Chemotherapy and radiation therapy, particularly those targeting reproductive organs, can damage the ovaries, leading to menopause. This is especially common in younger women undergoing cancer treatment for breast, ovarian, or other reproductive cancers.


  • Other Medical Interventions: Some medications used for managing conditions like endometriosis or fibroids can temporarily suppress ovarian function, causing menopausal symptoms. While these symptoms may reverse when treatment ends, they can be similar to those of menopause during treatment.


The Impact of Iatrogenic Menopause


The effects of iatrogenic menopause extend beyond physical symptoms. Women often face emotional and psychological challenges as they adjust to this abrupt transition. The sudden onset of symptoms can make it difficult for women to continue their daily activities, manage their professional lives, or maintain relationships. For those undergoing menopause due to cancer treatment, the experience can be particularly distressing, as they navigate both the menopause symptoms and the challenges of cancer recovery.


Because iatrogenic menopause can occur at a much younger age than natural menopause, it also brings unique concerns about long-term health, including the increased risk of heart disease, osteoporosis, and cognitive decline due to the prolonged period of estrogen deficiency. This makes it critical to adopt a proactive approach to managing the symptoms and minimizing long-term health risks.


Treatment Options for Iatrogenic Menopause


Managing iatrogenic menopause often requires a combination of medical treatments and lifestyle changes tailored to the individual's symptoms and overall health. Here are some options that can help women cope with its sudden onset:


  • Hormone Therapy (HT): Hormone therapy is often considered the most effective treatment for managing severe symptoms like hot flashes and vaginal dryness. It involves supplementing the body with estrogen, or a combination of estrogen and progesterone, to replace the hormones that the ovaries no longer produce. HT is typically recommended for younger women with iatrogenic menopause, as it can also help protect against osteoporosis and heart disease. However, it may not be suitable for all, especially those with a history of certain cancers.

  • Non-Hormonal Medications: For women who cannot use hormone therapy, non-hormonal medications, such as antidepressants or medications like gabapentin, can help manage symptoms like hot flashes and mood changes. Vaginal moisturizers and lubricants can also ease discomfort due to vaginal dryness.

  • Lifestyle Modifications: Adopting a healthy lifestyle can play a significant role in alleviating symptoms and improving overall well-being. Regular exercise, such as weight-bearing activities, helps maintain bone density and improves mood. A balanced diet rich in calcium and vitamin D can support bone health, while techniques like yoga and mindfulness can help manage stress and anxiety.

  • Bone Health Management: To mitigate the risk of osteoporosis, women experiencing iatrogenic menopause should consider supplements, such as calcium and vitamin D, and potentially medications that strengthen bone density. Regular bone density screenings are also recommended for early detection and prevention of bone loss.


Support and Coping Strategies


The journey through iatrogenic menopause can feel overwhelming, but support and understanding are key to managing this life stage. Women should not hesitate to reach out to healthcare providers who specialize in menopause management for personalized guidance. Joining support groups or connecting with others going through a similar experience can also be a valuable way to share insights and feel less isolated.


Managing Iatrogenic Menopause for a Healthier Future


While iatrogenic menopause can be a challenging experience, understanding its causes, symptoms, and treatment options can empower women to manage this life stage more effectively. A combination of medical support, lifestyle changes, and emotional resilience can help women regain their balance and focus on long-term well-being.


If you or someone you know is navigating the effects of iatrogenic menopause and looking for personalized care, Wellness MD is here to help. Our approach combines expert medical guidance with compassionate support, tailored to meet your unique needs. Contact us today to schedule a consultation and begin your journey towards healthier living.


— Reference:

Irene Lambrinoudaki, Eleni Armeni, Dimitrios Goulis, Silvia Bretz, Iuliana Ceausu, Fatih Durmusoglu, Risto Erkkola, Ivan Fistonic, Marco Gambacciani, Marije Geukes, Haitham Hamoda, Caiomhe Hartley, Angelica Lindén Hirschberg, Blazej Meczekalski, Nicolas Mendoza, Alfred Mueck, Antonina Smetnik, Petra Stute, Mick van Trotsenburg, Margaret Rees,

Menopause, wellbeing and health: A care pathway from the European Menopause and Andropause Society,

Maturitas,

Volume 163,2022,Pages 1-14,

ISSN 0378-5122,

(https://www.sciencedirect.com/science/article/pii/S0378512222000901)

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